Serie A: unavailable players, injured and suspended for matchday 6

Serie A clubs face multiple injury absences ahead of matchday 6: Milan's Saelemaekers requires ankle surgery (out until February), Bologna's Holm sidelined for five months after hamstring surgery.

Serie A clubs are dealing with a significant injury toll ahead of matchday 6. Milan's Alexis Saelemaekers requires ankle surgery and will miss at least until February due to instability from a previous fracture, while teammate Estupinian suffered a knee distortion with internal ligament damage. Bologna's Jens Holm underwent hamstring surgery and faces five months out. Other notable absences include Lazio's Gudmundsson (shoulder), Como's Kean (status unclear after missing Turkey match), and Roma's Cristante (knee, hoping to return for Champions League). Multiple other players are also sidelined across Serie A squads.